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HomeProduct name listDolutegravir 4-Desfluoro Impurity

Dolutegravir 4-Desfluoro Impurity

  • CAS NO.:1863916-87-3
  • Empirical Formula: C20H20FN3O5
  • Molecular Weight: 401.39
  • Update Date: 2022-12-21 16:56:50
Dolutegravir 4-Desfluoro Impurity Structural

What is Dolutegravir 4-Desfluoro Impurity?

The Uses of Dolutegravir 4-Desfluoro Impurity

4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Properties of Dolutegravir 4-Desfluoro Impurity

Boiling point: 671.6±55.0 °C(Predicted)
Density  1.49±0.1 g/cm3(Predicted)
pka 4.50±1.00(Predicted)

Safety information for Dolutegravir 4-Desfluoro Impurity

Computed Descriptors for Dolutegravir 4-Desfluoro Impurity

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