Docetaxel trihydrate

CAS NO.：148408-66-6
Empirical Formula: C43H55NO15
Molecular Weight: 825.91
EINECS: 642-361-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is Docetaxel trihydrate?

Chemical properties

White Crystalline Powder

The Uses of Docetaxel trihydrate

Docetaxel Trihydrate is an anti-cancer drugs; Semisynthetic analog of the taxane paclitaxel.

The Uses of Docetaxel trihydrate

An antineoplastic. An antimitotic agent that promotes the assembly of microtublules and inhibits their depolymerization to free tubulin

What are the applications of Application

Docetaxel Trihydrate is an antineoplastic and antimitotic agent that promotes the assembly of microtubules

Definition

ChEBI: The trihydrate form of docetaxel. It is used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.

brand name

Taxotere (Sanofi Aventis).

Properties of Docetaxel trihydrate

Melting point:	186-192°C
storage temp.	2-8°C
solubility	Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in methylene chloride.
form	neat
form	Solid
color	White to OFf-White
Stability:	Hygroscopic
CAS DataBase Reference	148408-66-6(CAS DataBase Reference)

Safety information for Docetaxel trihydrate

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.