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HomeProduct name listDocetaxel trihydrate

Docetaxel trihydrate

Docetaxel trihydrate Structural

What is Docetaxel trihydrate?

Chemical properties

White Crystalline Powder

The Uses of Docetaxel trihydrate

Docetaxel Trihydrate is an anti-cancer drugs; Semisynthetic analog of the taxane paclitaxel.

The Uses of Docetaxel trihydrate

An antineoplastic. An antimitotic agent that promotes the assembly of microtublules and inhibits their depolymerization to free tubulin

What are the applications of Application

Docetaxel Trihydrate is an antineoplastic and antimitotic agent that promotes the assembly of microtubules

Definition

ChEBI: The trihydrate form of docetaxel. It is used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.

brand name

Taxotere (Sanofi Aventis).

Properties of Docetaxel trihydrate

Melting point: 186-192°C
storage temp.  2-8°C
solubility  Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in methylene chloride.
form  neat
form  Solid
color  White to OFf-White
Stability: Hygroscopic
CAS DataBase Reference 148408-66-6(CAS DataBase Reference)

Safety information for Docetaxel trihydrate

Signal word Danger
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H319:Serious eye damage/eye irritation
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313:IF exposed or concerned: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for Docetaxel trihydrate

InChIKey XCDIRYDKECHIPE-KHDBCEGQSA-N

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