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HomeProduct name listDMT-2'O-Methyl-rU Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite

Synonym(s):5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-uridine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];DMT-2′O-Methyl-rU amidite

  • CAS NO.:110764-79-9
  • Empirical Formula: C40H49N4O9P
  • Molecular Weight: 760.82
  • MDL number: MFCD00792626
  • EINECS: 200-100-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-12-13 10:50:56
DMT-2'O-Methyl-rU Phosphoramidite Structural

What is DMT-2'O-Methyl-rU Phosphoramidite?

The Uses of DMT-2'O-Methyl-rU Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite is a white to off-white powder and is used as a pharmaceutical intermediate for pharmaceutical synthesis and scientific research.

What are the applications of Application

2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rU Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules

Properties of DMT-2'O-Methyl-rU Phosphoramidite

storage temp.  Sealed in dry,2-8°C
solubility  DMSO : 100 mg/mL (131.44 mM; Need ultrasonic)
pka 9.39±0.10(Predicted)
form  powder
color  white to off-white

Safety information for DMT-2'O-Methyl-rU Phosphoramidite

Computed Descriptors for DMT-2'O-Methyl-rU Phosphoramidite

InChIKey UVUOJOLPNDCIHL-XKZJCBTISA-N
SMILES C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,36,39,r|

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