DL-Pipecolinic acid

Synonym(s):(±)-Piperidine-2-carboxylic acid;2-Piperidinecarboxylic acid;Homoproline;Pipecolic acid free base

CAS NO.：535-75-1
Empirical Formula: C6H11NO2
Molecular Weight: 129.16
MDL number: MFCD00064347
EINECS: 208-616-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-19 17:35:41

What is DL-Pipecolinic acid?

Chemical properties

white to light beige fine crystalline powder

The Uses of DL-Pipecolinic acid

DL-Pipecolinic acid is used as a diagnostic marker of pyridoxine-dependent epilepsy. It acts as a ligand in copper-catalyzed approach for P-arylation of organophosphorus compounds. It is used as organocatalyst and novel substrate in organic synthesis.

The Uses of DL-Pipecolinic acid

Pipecolic acid is involved in synaptic transmission in the central nervous system.

Definition

ChEBI: A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.

Properties of DL-Pipecolinic acid

Melting point:	282 °C (dec.)(lit.)
Boiling point:	239.22°C (rough estimate)
alpha	[α]D20 -1～+1° (c=2.5, H2O)
Density	1.1426 (rough estimate)
refractive index	1.4587 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Methanol (Slightly), Water (Slightly)
pka	2.28, 10.72(at 25℃)
form	Fine Crystalline Powder
color	White to light beige
Water Solubility	soluble
Merck	14,7458
BRN	81095
CAS DataBase Reference	535-75-1(CAS DataBase Reference)
EPA Substance Registry System	2-Piperidinecarboxylic acid (535-75-1)

Safety information for DL-Pipecolinic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.