DL-Mandelic acid
Synonym(s):(±)-α-Hydroxyphenylacetic acid;DL-α-Hydroxyphenylacetic acid, Phenylglycollic acid;DL-Mandelic acid
- CAS NO.：611-72-3
- Empirical Formula: C8H8O3
- Molecular Weight: 152.15
- MDL number: MFCD00064250
- EINECS: 202-007-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-15 19:19:13
What is DL-Mandelic acid?
Chemical properties
Mandelic acid turns brown when exposed to light. It can be esterified easily with alcohols in the presence of hydrogen chloride.
Physical properties
(R,S)-Mandelic acid (a-hydroxyphenylacetic acid, phenylglycolic acid), C6H5CH(OH)COOH, C8H8O3, Mr 152.15, mp 118 – 121℃, is a colorless crystalline powder. It is readily soluble in ethanol and diethyl ether, less soluble in chloroform, and insoluble in petroleum ether. Its water solubility is 15 g per 100 mL of water. In alkaline solution, mandelic acid dissolves to form salts.
Definition
ChEBI: Mandelic acid is a 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups. It has a role as an antibacterial agent and a human xenobiotic metabolite. It is a 2-hydroxy monocarboxylic acid and a member of benzenes. It is functionally related to an acetic acid. It is a conjugate acid of a mandelate.
Production Methods
(R,S)-mandelic acid is produced by hydrolysis of mandelic acid nitrile [532-28-5] (mp 10℃) with hydrochloric acid. Mandelic acid nitrile is obtained by the conversion of benzaldehyde [100-52-7] and hydrogen cyanide in the nascent state (NaCN + HCl) under refrigeration. Another method of producing mandelic acid is the hydrolysis of a,a-dichloroacetophenone with alkali.
Properties of DL-Mandelic acid
| Melting point: | 119-121 °C(lit.) |
| Boiling point: | 234.6°C (rough estimate) |
| Density | 1.2890 |
| refractive index | 1.4945 (estimate) |
| pka | 3.85(at 25℃) |
| Water Solubility | 172.5g/L(24 ºC) |
| CAS DataBase Reference | 611-72-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzeneacetic acid, «alpha»-hydroxy-, (.+/-.)-(611-72-3) |
Safety information for DL-Mandelic acid
Computed Descriptors for DL-Mandelic acid
DL-Mandelic acid manufacturer
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
You may like
-
Powder Dl Mandelic Acid, For Anti Infective, Grade: Pharma GradeView Details
611-72-3 -
DL-Mandelic Acid CAS 611-72-3View Details
611-72-3 -
Dl-Mandelic Acid, 99% PureView Details
90-64-2 -
Dl Mandelic Acid, 25kg, 98% PureView Details
90-64-2 -
DL-MANDELIC ACIDView Details
90-64-2 -
Powder Dl Mandelic Acid, Purity: 99%, Grade Standard: CosmeticView Details
611-72-3 -
Pyridine 99.5% HPLC /UV SpectroscopyView Details
110-86-1 -
Thiourea 99% ARView Details
62-56-6