DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
Synonym(s):(±)-AP-4
- CAS NO.：20263-07-4
- Empirical Formula: C4H10NO5P
- Molecular Weight: 183.1
- MDL number: MFCD00013999
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID?
The Uses of DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies.
What are the applications of Application
DL-2-Amino-4-phosphonobutanoic acid (AP4) is an amino-acid derivative reported to block cone signals in the rat retina
General Description
(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs.
Biological Activity
Broad spectrum EAA ligand. See separate isomers (D-(-)-2-Amino-4-phosphonobutyric acid and L-(+)-2-Amino-4-phosphonobutyric acid).
Properties of DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
| Melting point: | 225 °C |
| storage temp. | 0-6°C |
| form | solid |
| color | white |
| Water Solubility | Soluble to 33 mM in water |
| BRN | 2093908 |
| CAS DataBase Reference | 20263-07-4(CAS DataBase Reference) |
Safety information for DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
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![[3H]-(L)-AP4](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB7755385.gif)
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