Dizocilpine
- CAS NO.：77086-21-6
- Empirical Formula: C16H15N
- Molecular Weight: 221.3
- MDL number: MFCD06412575
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Dizocilpine?
The Uses of Dizocilpine
Neuroprotective.
Definition
ChEBI: Dizocilpine is an organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. It has a role as a NMDA receptor antagonist, an anaesthetic, an anticonvulsant, a nicotinic antagonist and a neuroprotective agent. It is a secondary amino compound and a tetracyclic antidepressant. It is a conjugate base of a dizocilpine(1+).
Properties of Dizocilpine
| Melting point: | 68.5-69° |
| Boiling point: | 320.3±11.0 °C(Predicted) |
| alpha | 20589 +161.4° (c = 0.038 g/2 ml ethanol) |
| Density | 1.144±0.06 g/cm3(Predicted) |
| solubility | Soluble in DMSO > 10 mM |
| form | Powder |
| pka | 7.96±0.40(Predicted) |
| EPA Substance Registry System | 5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)- (77086-21-6) |
Safety information for Dizocilpine
Computed Descriptors for Dizocilpine
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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