Disodium phosphonomycin

Synonym(s):(−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid;Fosfomycin;Phosphomycin disodium salt;Phosphonomycin

CAS NO.：26016-99-9
Empirical Formula: C3H8NaO4P
Molecular Weight: 162.06
MDL number: MFCD00056853
EINECS: 247-409-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

What is Disodium phosphonomycin?

Chemical properties

White Solid

The Uses of Disodium phosphonomycin

Disodium phosphonomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine

The Uses of Disodium phosphonomycin

Curariform muscle relaxants

The Uses of Disodium phosphonomycin

Prevents peptidoglycan synthesis by inhibiting MurA, an enzyme responsible for synthesizing N-acetylmuramic acid or NAM, a major component of peptidoglycan

What are the applications of Application

Fosfomycin Disodium Salt is an antibiotic enzyme inhibitor

Properties of Disodium phosphonomycin

Melting point:	>300°C
storage temp.	Inert atmosphere,2-8°C
solubility	H₂O: 50 mg/mL, clear, colorless
form	neat
form	Solid
color	White to Off-White
Water Solubility	Freely soluble in water or aqueous solution
BRN	4604425
Stability:	Hygroscopic
CAS DataBase Reference	26016-99-9(CAS DataBase Reference)

Safety information for Disodium phosphonomycin

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H303:Acute toxicity,oral
Precautionary Statement Codes	P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P403:Store in a well-ventilated place.