Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)
- CAS NO.：20324-87-2
- Empirical Formula: C21H17N2NaO9S2
- Molecular Weight: 528.48
- MDL number: MFCD00068249
- EINECS: 243-735-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-30 21:47:27
What is Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)?
The Uses of Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)
AMI-1 is a Histone Methyltransferase (HMT) inhibitor.
What are the applications of Application
AMI-1, sodium salt is a PRMT and HIV-1 RT polymerase inhibitor
Biological Activity
potent, cell permeable and specific protein arginine n-methyltransferase 1 (prmt1) inhibitor (ic50 = 8, 8 μm), does not compete for the adomet (s-adenosyl-l-methionine, sam) binding site, blocks peptide substrate binding, hiv-1 rt polymerase inhibitor (ic50 = 5, 0 μm).
Properties of Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL in H2O |
| form | Brown solid. |
| color | Light brown to brown |
| EPA Substance Registry System | 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-, disodium salt (20324-87-2) |
Safety information for Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)
Computed Descriptors for Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)
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