Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)

CAS NO.：20324-87-2
Empirical Formula: C21H17N2NaO9S2
Molecular Weight: 528.48
MDL number: MFCD00068249
EINECS: 243-735-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-30 21:47:27

What is Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)?

The Uses of Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)

AMI-1 is a Histone Methyltransferase (HMT) inhibitor.

What are the applications of Application

AMI-1, sodium salt is a PRMT and HIV-1 RT polymerase inhibitor

Biological Activity

potent, cell permeable and specific protein arginine n-methyltransferase 1 (prmt1) inhibitor (ic50 = 8, 8 μm), does not compete for the adomet (s-adenosyl-l-methionine, sam) binding site, blocks peptide substrate binding, hiv-1 rt polymerase inhibitor (ic50 = 5, 0 μm).

Properties of Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)

storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL in H2O
form	Brown solid.
color	Light brown to brown
EPA Substance Registry System	2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-, disodium salt (20324-87-2)

Safety information for Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)

Computed Descriptors for Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)

New Products

4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acid

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