DIPERODON
- CAS NO.:101-08-6
- Empirical Formula: C22H27N3O4
- Molecular Weight: 397.47
- MDL number: MFCD00864459
- EINECS: 202-913-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 17:36:06
What is DIPERODON?
Originator
Diothane Hydrochloride,HMR
Definition
ChEBI: N-phenylcarbamic acid [2-[anilino(oxo)methoxy]-3-(1-piperidinyl)propyl] ester is a carbamate ester.
Manufacturing Process
15.0 g phenylisocyanate in 100 ml of anhydrous ether are added to 10 g of N- (1,2-dihydroxypropyl)-piperidine (prepared from glycide and piperidine) and the solution boiled for two hours, after which it is cooled and saturated with dry hydrogen chloride gas. The ether layer is then decanted off and the remaining insoluble product is dissolved in a hot mixture of acetone and ethyl acetate which on cooling precipitates white crystals of the hydrochloride of the ester of 1,2-propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate); MP 197°- 198°C. A base form may be prepared by adding an equivalent of triethyl amine.
Therapeutic Function
1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate) (ester), hydrochloride
Properties of DIPERODON
Boiling point: | 520.91°C (rough estimate) |
Density | 1.2228 (rough estimate) |
refractive index | 1.6500 (estimate) |
pka | pKa 8.44(H2O) (Occasionally) |
Safety information for DIPERODON
Computed Descriptors for DIPERODON
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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