DIMINAZENE ACETURATE
Synonym(s):Berenil
- CAS NO.：908-54-3
- Empirical Formula: C22H29N9O6
- Molecular Weight: 515.52
- MDL number: MFCD00058386
- EINECS: 212-999-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is DIMINAZENE ACETURATE?
Description
Diminazene is a diamidine that is cytotoxic to protozoa, including Trypanosoma, Babesia, and Cytauxzoon. Diamidines, including diminazene, affect a variety of enzymes and modulate interactions between nucleic acids and proteins. Diminazene inhibits diamine oxidase with a Ki value of 13 nM. In Trypanosoma, transport proteins are important in the effectiveness of diminazene. In rats and in vitro, diminazene enhances the enzymatic activity of angiotensin-converting enzyme 2.
Chemical properties
solid
The Uses of DIMINAZENE ACETURATE
Diminazene aceturate is an anti-protozoal drug. Diminazene Diaceturate is used as an anti-trypanosomal agent.
The Uses of DIMINAZENE ACETURATE
antiprotozoal as aceturate
The Uses of DIMINAZENE ACETURATE
An anti-protozoal and anti-trypanosomal compound
What are the applications of Application
Diminazene Aceturate is an anti-protozoal and anti-trypanosomal diamidine that affects a variety of enzymes.
Definition
ChEBI: An N-acetylglycinate salt resulting from the reaction of diminazene with 2 mol eq. of N-acetylglycine.
Veterinary Drugs and Treatments
Diminazene is used to treat trypanosomiasis in dogs and livestock (sheep, goats, cattle), Babesia infections in dogs and horses, and cytauxzoonosis in cats. The drug is not commercially available in the USA, but is available and used in many countries.
storage
Store at RT
Properties of DIMINAZENE ACETURATE
| Melting point: | 202 °C |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | powder |
| color | Orange to Dark Orange |
| Water Solubility | Soluble to 100 mM in water |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 908-54-3(CAS DataBase Reference) |
Safety information for DIMINAZENE ACETURATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DIMINAZENE ACETURATE
DIMINAZENE ACETURATE manufacturer
Rakshit Group of Companies (Rakshit Drugs Pvt Ltd)
Nulli Secondus Impex Pvt Ltd
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