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HomeProduct name listDifenoconazole

Difenoconazole

Difenoconazole Structural

What is Difenoconazole?

Description

Difenoconazole is a kind of triazole-type fungicide. It is a broad-spectrum triazole fungicide. It takes effect through acting as the inhibitor of sterol 14α-demethylase, blocking the biosynthesis of sterol. Through inhibiting the sterol biosynthesis process, it inhibits the mycelia growth and germination of pathogens by spores, ultimately suppressing the proliferation of fungi. Difenoconazole has been extensively used in a wide range of crops in many countries due to its ability to control various fungal diseases. It is also one of the most important and widely-used pesticides for disease control in rice.

The Uses of Difenoconazole

Difenoconazole is a fungicide with broad-range activity, protecting yield and quality by foliar application or seed treatment. It provides long-lasting and curative activity against Ascomycetes, Basidiomycetes and Deuteromycetes. It is used against disease complexes in grapes, pome fruit, stone fruit, potatoes, sugar beet, oilseed rape, banana, ornamentals and various vegetable crops. It is also used as a seed treatment against a range of pathogens in wheat and barley.

The Uses of Difenoconazole

Pestanal is an fungicide that exhibits a broad spectrum of activities against a wide variety of fungi including members of the Aschomycetes, Basidomycetes and Deuteromycetes families.

The Uses of Difenoconazole

Agricultural fungicide.

What are the applications of Application

Difenoconazole is a compound that metabolizes glucosinolates which increase the production of isothiocyanates

Definition

ChEBI: A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms.

Agricultural Uses

Fungicide: For suppression of fungi diseases in crops and seeds.

Trade name

CGA 169374®; DIVIDEND®; DIVIDEND® EXTREME FUNGICIDE; HELIX®; SCORE®; TECHNICAL CGA-169374®

Metabolic pathway

There is limited published information on the metabolism of difenoconazole. It is slowly dissipated in soils, and metabolism in plants involves rupture of the triazole linkage or oxidation of the phenyl ring followed by conjugation.

Degradation

Difenoconazole is stable to hydrolysis and is thermally stable to 150 °C. DT50 of difenocoazole in natural sunlight was 145 days.

References

Kwok, Iris M‐Y., and R. Thomas Loeffler. "The biochemical mode of action of some newer azole fungicides." Pest Management Science 39.1 (1993): 1-11.
Wang, K., J. X. Wu, and H. Y. Zhang. "Dissipation of difenoconazole in rice, paddy soil, and paddy water under field conditions." Ecotoxicology and environmental safety 86 (2012): 111-115.

Properties of Difenoconazole

Melting point: 76°C
Boiling point: 220°C
Density  1.4916 (rough estimate)
vapor pressure  3.3 x l0-8 Pa (25 °C)
refractive index  1.6140 (estimate)
storage temp.  Keep in dark place,Sealed in dry,2-8°C
solubility  Chloroform: Slightly Soluble,Methanol: Slightly Soluble
form  neat
pka 2.94±0.12(Predicted)
form  Solid
color  White to off-white
Water Solubility  3.3 mg/L (20 ºC)
Merck  13,3160
BRN  9073356
CAS DataBase Reference 119446-68-3(CAS DataBase Reference)
NIST Chemistry Reference Difenoconazole(119446-68-3)
EPA Substance Registry System Difenoconazole (119446-68-3)

Safety information for Difenoconazole

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H319:Serious eye damage/eye irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Difenoconazole

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