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HomeProduct name listDiethyl methylphosphonate

Diethyl methylphosphonate

Synonym(s):Bis(diethoxyphosphinyl)methane;DEMP;Diethoxymethylphosphine oxide

  • CAS NO.:683-08-9
  • Empirical Formula: C5H13O3P
  • Molecular Weight: 152.13
  • MDL number: MFCD00009813
  • EINECS: 211-667-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
Diethyl methylphosphonate Structural

What is Diethyl methylphosphonate?

Chemical properties

clear colorless liquid

The Uses of Diethyl methylphosphonate

Diethyl methylphosphonate is used as a precursor for the synthesis of gem-difluroalkenyphosphonate via reaction with alpha-trifluromethylstyrene. It is also used in the synthesis of phosphonylated peptides, fluoroalkyl alpha- and beta-aminophosphonates, pyridone alkaloids with neuritogenic activity and lipophilic meropenem-derived prodrugs. It is readily mineralized by photoexcited titanium dioxide (TiO2).

Properties of Diethyl methylphosphonate

Boiling point: 194 °C(lit.)
Density  1.041 g/mL at 25 °C(lit.)
refractive index  n20/D 1.414(lit.)
Flash point: 168 °F
storage temp.  Hygroscopic, Refrigerator, under inert atmosphere
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Liquid
color  Clear colorless to pale yellow
Water Solubility  Miscible with water.
BRN  1753416
Stability: Hygroscopic
CAS DataBase Reference 683-08-9(CAS DataBase Reference)
NIST Chemistry Reference Diethyl methanephosphonate(683-08-9)

Safety information for Diethyl methylphosphonate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Diethyl methylphosphonate

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