DIDS
- CAS NO.:67483-13-0
- Empirical Formula: C16H8N2Na2O6S4
- Molecular Weight: 498.48
- MDL number: MFCD00009638
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-04 15:51:00
What is DIDS?
Chemical properties
yellow to yellow-green or brown powder
The Uses of DIDS
Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle. Fluorescence: max. Abs. l = 341, max. Em. l = 415 (in water)
The Uses of DIDS
ATP transport inhibitor, anion transport inhibitor, antiulcer
The Uses of DIDS
complexing agent for potassium ions
The Uses of DIDS
DIDS is a stilbene sulfonate that inhibits anionic transport. It has been used to inhibit Cl- uptake through plasma membrane-localized Cl- channels in order to study chloride transport. It also effectively inhibits various sodium-coupled bicarbonate transporters.
What are the applications of Application
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt is a negatively charged homobifunctional cross-linking reagent and dye
What are the applications of Application
DIDS, Disodium Salt is an anion transport inhibitor that inhibits Cl- uptake through plasma membrane-localized Cl- channels.
storage
Store at +4°C
Properties of DIDS
Melting point: | >300°C |
Density | 1.54 |
storage temp. | 2-8°C |
solubility | 0.1 M potassium bicarbonate: 50 mg/mL |
form | powder |
color | yellow |
Stability: | Recommend Desiccate and Storage at -20°C |
CAS DataBase Reference | 67483-13-0 |
Safety information for DIDS
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for DIDS
New Products
2,2-diethoxyethanethioamide (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin I Tubulysin D Tubulysin H 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2,2-Difluoropropylamine hydrochloride CYCLOBUTYLAMINE HYDROCHLORIDE Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 2,2-Difluoropropanol 4,4-DIFLUOROPIPERIDINE (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Fuel shell Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
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