Dichloro(1,5-cyclooctadiene)palladium(II)

Synonym(s):PdCl₂(cod)

CAS NO.：12107-56-1
Empirical Formula: C8H12Cl2Pd
Molecular Weight: 285.51
MDL number: MFCD00012412
EINECS: 235-161-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-09-12 12:58:44

Dichloro(1,5-cyclooctadiene)palladium(II) Structural

What is Dichloro(1,5-cyclooctadiene)palladium(II)?

Chemical properties

yellow

The Uses of Dichloro(1,5-cyclooctadiene)palladium(II)

Dichloro(1,5-cyclooctadiene)palladium(II) is a commonly used catalyst to protect alcohols as acetals by treating with 2-benzyloxy-1-propene; to synthesize bicyclooctanes from diethyl malonate and in alkene carbonylation. It can also be used to catalyze the Heck coupling of nonactivated vinyl phosphates with electron deficient alkenes; the synthesis of benzo[b]thiophenes from thioenols and to prepare an active catalyst for Mizoroki-Heck and Suzuki-Miyaura cross-coupling reactions.

The Uses of Dichloro(1,5-cyclooctadiene)palladium(II)

Dichloro(1,5-cyclooctadiene)palladium(II) is used as catalyst for C-C bond and C-N formation, used in Heck coupling of alkynes with alkenes, Suzuki cross-coupling of aryl bromides , allylic substitution of oximes with allylic acetate and methoxycarbonylation of iodobenzene.

Properties of Dichloro(1,5-cyclooctadiene)palladium(II)

Melting point:	210 °C (dec.) (lit.)
storage temp.	Inert atmosphere,Room Temperature
solubility	Soluble in dichloromethane
form	crystal
color	yellow
Water Solubility	insoluble
Sensitive	Hygroscopic
CAS DataBase Reference	12107-56-1(CAS DataBase Reference)
EPA Substance Registry System	Palladium, dichloro[(1,2,5,6-.eta.)-1,5-cyclooctadiene]- (12107-56-1)

Safety information for Dichloro(1,5-cyclooctadiene)palladium(II)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.