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HomeProduct name listDi-tert-butyl N,N-diisopropylphosphoramidite

Di-tert-butyl N,N-diisopropylphosphoramidite

Di-tert-butyl N,N-diisopropylphosphoramidite Structural

What is Di-tert-butyl N,N-diisopropylphosphoramidite?

Chemical properties

Clear Colourless Liquid

The Uses of Di-tert-butyl N,N-diisopropylphosphoramidite

A phosphinane derivative with immunomodulating activity.

The Uses of Di-tert-butyl N,N-diisopropylphosphoramidite

Di-tert-butyl N,N-diisopropylphosphoramidite is a general reagent to introduce tert-butyl-protected phosphate groups. It is commonly used in phosphorylation of biomolecules. It can also be used in the synthesis of phosphoramidate-linked glycoconjugates.

Properties of Di-tert-butyl N,N-diisopropylphosphoramidite

Boiling point: 85-90 °C/0.2 mmHg (lit.)
Density  0.879 g/mL at 25 °C (lit.)
refractive index  n20/D 1.444(lit.)
Flash point: >230 °F
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
pka 4.90±0.70(Predicted)
form  Liquid
color  Clear colorless
BRN  4858847
Stability: Moisture Sensitive
CAS DataBase Reference 137348-86-8(CAS DataBase Reference)

Safety information for Di-tert-butyl N,N-diisopropylphosphoramidite

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Di-tert-butyl N,N-diisopropylphosphoramidite

InChIKey YGFLCNPXEPDANQ-UHFFFAOYSA-N

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