Deslanoside
Synonym(s):Deacetyllanatoside C;Desacetyllanatoside C
- CAS NO.：17598-65-1
- Empirical Formula: C47H74O19
- Molecular Weight: 943.08
- MDL number: MFCD00135818
- EINECS: 241-568-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:14
What is Deslanoside?
Absorption
Little absorption from the gastrointestinal tract (40%).
Toxicity
Symptoms of overdose include ventricular tachycardia, ventricular fibrillation, progressive bradyarrhythmias, or heart block.
Chemical properties
Solution S is clear (2.2.1) and colourless (2.2.2, Method II).
The Uses of Deslanoside
Cardiotonic.
Indications
For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
Background
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Definition
ChEBI: A cardenolide glycoside that is lanatoside C with the acetoxy group replaced by a hydroxy group.
brand name
Cedilanid-D (Novartis).
Pharmacokinetics
Deslanoside is a cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.
Metabolism
Not Available
Properties of Deslanoside
| Melting point: | 220-235°C |
| alpha | D20 +12° (c = 1.084 in 75% alc) |
| Boiling point: | 732.1°C (rough estimate) |
| Density | 1.1255 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml |
| form | Solid |
| pka | 12.89±0.70(Predicted) |
| form | neat |
| color | White to off-white |
| CAS DataBase Reference | 17598-65-1(CAS DataBase Reference) |
Safety information for Deslanoside
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P314:Get medical advice/attention if you feel unwell. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for Deslanoside
Deslanoside manufacturer
Deccan Nutraceuticals Pvt. Ltd
1Y
Phone:+91-9822641298
Whatsapp: +91 9822641298
product: 17598-65-1 Deslanoside 98%
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