DEA
- CAS NO.：150314-35-5
- Empirical Formula: C24H41NO2
- Molecular Weight: 375.59
- MDL number: MFCD09878239
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:09
What is DEA?
Description
Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA. However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated.
The Uses of DEA
(7Z,10Z,13Z,16Z)-N-(2-Hydroxyethyl)-7,10,13,16-docosatetraenamide is an endocannabinoid and an analog of anandamide, which is an endogenous cannabinoid and TRPV1 receptor agonist.
What are the applications of Application
DEA is an endocannabinoid agonist of the CB1 receptor
Definition
ChEBI: 7,10,13,16-Docosatetraenoylethanolamine is a N-acylethanolamine 22:4.
Biological Activity
Potent endocannabinoid ( anandamide analog) that activates CB 1 receptors in microglia and binds to rat synaptosomal membranes (K I = 34.4 nM). Cannabimimetic in vivo .
Properties of DEA
| Boiling point: | 544.5±50.0 °C(Predicted) |
| Density | 0.932±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 30 mg/ml; Ethanol: 100 mg/ml; Ethanol:PBS (1:2): 8 mg/ml; PBS (pH 7.2): <100 μg/ml |
| pka | 14.49±0.10(Predicted) |
Safety information for DEA
Computed Descriptors for DEA
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![ANANDAMIDE [ETHANOLAMINE 1,2-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure5/GIF/CB5701409.gif)
![ANANDAMIDE, [ARACHIDONYL-1-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB6403155.gif)
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