DAMASCONE

Synonym(s):(E)-1-(2,6,6-Trimethyl-1-cyclohexenyl)-2-buten-1-one

CAS NO.：23726-91-2
Empirical Formula: C13H20O
Molecular Weight: 192.3
MDL number: MFCD00661756
EINECS: 245-842-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-07 21:39:59

What is DAMASCONE?

The Uses of DAMASCONE

(E)-β-Damascone is an odorant found in some food, tea and tobacco plants. It is found to inhibit lipopolysaccharide mediated nitric oxide production through nuclear factor E2-related protein 2 signaling in human colon adenocarcinoma and mouse macrophage.

Definition

ChEBI: 4-(2,6,6-Trimethylcyclohex-1-enyl)but-2-en-4-one is an enone.

Synthesis Reference(s)

Journal of the American Chemical Society, 94, p. 9128, 1972 DOI: 10.1021/ja00781a023

Flammability and Explosibility

Non flammable

Properties of DAMASCONE

Boiling point:	271℃
Density	0.934 g/mL at 20 °C(lit.)
vapor pressure	2.6Pa at 25℃
refractive index	n20/D 1.498
FEMA	3243 \| 1-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2-BUTEN-1-ONE
Flash point:	108℃
storage temp.	-20°C
solubility	Chloroform (Slightly), DMSO (Slightly)
form	Oil
color	Colourless to Pale Yellow
Odor	at 1.00 % in dipropylene glycol. fruity floral berry plum blackcurrant honey rose tobacco
Water Solubility	192.3mg/L(25 ºC)
JECFA Number	384
BRN	2046078
Stability:	Light Sensitive
EPA Substance Registry System	2-Buten-1-one, 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (2E)- (23726-91-2)

Safety information for DAMASCONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.