D-Phenylglycinol

Synonym(s):(R)-2-Amino-2-phenylethanol;D-(−)-α-Phenylglycinol

CAS NO.：56613-80-0
Empirical Formula: C8H11NO
Molecular Weight: 137.18
MDL number: MFCD00008062
EINECS: 260-287-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-03 14:46:32

What is D-Phenylglycinol?

Chemical properties

white to light yellow crystal powder.

The Uses of D-Phenylglycinol

As a chiral arylalkylamine used as organocatalysts, D-Plenylglycinol can be used in the synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.

The Uses of D-Phenylglycinol

A chiral arylalkylamine used as organocatalysts. Used in the synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.

What are the applications of Application

(R)-(?)-2-Phenylglycinol is a useful stereodefined starting material

Definition

ChEBI: (R)-(-)-2-Phenylglycinol is an aralkylamine.

Preparation

D-Phenylglycinol was synthesized by reducing D-phenylglycine using a sodium borohydride-iodine system. The best reaction conditions were using tetrahydrofuran as the solvent, a 1:2 ratio of D-phenylglycine to sodium borohydride, a hydrolysis temperature of 50°C, and a reaction time of 20 hours.

Properties of D-Phenylglycinol

Melting point:	76-79 °C
Boiling point:	252.03°C (rough estimate)
alpha	-25.5 º (c=6,MeOH)
Density	1.0630 (rough estimate)
refractive index	-29.5 ° (C=1, EtOH)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Aqueous Acid (Slightly, Sonicated), Chloroform (Sparingly, Heated), Methanol (Slightly)
pka	12.51±0.10(Predicted)
form	Crystalline Powder
color	White to yellow
optical activity	[α]24/D 31.7°, c = 0.76 in 1 M HCl
Water Solubility	Slightly soluble in water.
Sensitive	Air Sensitive
BRN	2935848
CAS DataBase Reference	56613-80-0(CAS DataBase Reference)
NIST Chemistry Reference	(R)-(-)-2-phenylglycinol(56613-80-0)

Safety information for D-Phenylglycinol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.