D-(-)-MANDELIC ACID BENZYL ESTER
- CAS NO.:97415-09-3
- Empirical Formula: C15H14O3
- Molecular Weight: 242.27
- MDL number: MFCD00674031
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:01:56
What is D-(-)-MANDELIC ACID BENZYL ESTER?
Description
(R)-
The Uses of D-(-)-MANDELIC ACID BENZYL ESTER
D-(-)-Mandelic Acid Benzyl Ester is a useful reagent for the preparation of a pharmaceutical composition for treating atopic dermatitis.
The Uses of D-(-)-MANDELIC ACID BENZYL ESTER
Benzyl (R)-(-)-mandelate can be employed as reactant to synthesize:
- (S)-α-Hydroxy-N-(2-phenylethyl)benzenepropanamide (α-hydroxyamides) by enzyme catalyzed amidation reaction.
- Optically pure (R)- monomethyl esters of 3-[(tert-butyldimethylsilyl)oxy]pentanedioic acid, which is employed in the preparation of HMG-CoA reductase inhibitors.
- O-Ibuprofenylmandelic acid via acylation reaction with optically active ibuprofen and subsequent hydrogenation.
- Benzyl (R)-2-fluoro-2-phenylacetate via deoxyfluorination of alcohols using AlkylFluor.
What are the applications of Application
(R)-benzyl Mandelate is a synthetic intermediate
Properties of D-(-)-MANDELIC ACID BENZYL ESTER
Melting point: | 104-107 °C(lit.) |
Boiling point: | 387℃ |
Density | 1.204 |
refractive index | -34 ° (C=1, CH3CN) |
Flash point: | 163℃ |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml; DMSO: 25 mg/ml; Ethanol: 20 mg/ml |
pka | 12.15±0.20(Predicted) |
form | powder to crystal |
color | White to Almost white |
optical activity | [α]25/D 55°, c = 1 in chloroform |
CAS DataBase Reference | 97415-09-3 |
Safety information for D-(-)-MANDELIC ACID BENZYL ESTER
Computed Descriptors for D-(-)-MANDELIC ACID BENZYL ESTER
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
L-(+)-MANDELIC ACID BENZYL ESTER
PHENYL ACETATE
DL-MANDELIC ACID BENZYL ESTER 98+%,mandelic acid benzyl ester
Mandelic acid
(S)-(+)-Mandelic acid
D-(-)-MANDELIC ACID BENZYL ESTER
DL-MANDELIC ACID BENZYL ESTER
(R)-3-Hydroxypiperidine hydrocloride
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