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HomeProduct name listD-Luciferin sodium salt

D-Luciferin sodium salt

Synonym(s):(S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid sodium salt;4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt;Firefly luciferin sodium salt

  • CAS NO.:103404-75-7
  • Empirical Formula: C11H9N2NaO3S2
  • Molecular Weight: 304.31
  • MDL number: MFCD00044938
  • EINECS: 600-430-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 21:24:55
D-Luciferin sodium salt Structural

What is D-Luciferin sodium salt?

Description

D-Luciferin is a chemiluminescent substrate of firefly luciferase. It produces light upon oxidative decarboxylation by luciferase in the presence of ATP. D-luciferin can be employed to assay the expression of the luciferase gene linked to a promoter of interest. Alternatively, D-luciferin and luciferase can be used to assess ATP availability in cellular or biochemical assays.

Chemical properties

Yellow powder

The Uses of D-Luciferin sodium salt

D-Luciferin sodium salt is substrate for firefly luciferase, properties and use in assays of ATP and luciferase.

The Uses of D-Luciferin sodium salt

Luciferin is used for luciferase assays and determination of ATP.

The Uses of D-Luciferin sodium salt

D-Luciferin sodium salt has been used as a substrate in luciferin?luciferase chemiluminescence assay to determine ATP levels.

What are the applications of Application

D-Luciferin sodium salt is a substrate that produces bioluminescence upon oxidation by the enzyme luciferase

What are the applications of Application

D-Luciferin, sodium salt monohydrate is a bioluminescent compound

General Description

D-Luciferin is mainly produced in bioluminescent organisms. It can simply circulate across the blood testis barrier, blood brain barrier and the blood placenta barrier. This small molecule is sensitive to light and oxygen. D-Luciferin is also sensitive to moisture in its powder form.

Biological Activity

D-Luciferin sodium salt is a firefly luciferase substrate (Km = ~2 μM). Used in much standard bioluminescence imaging (BLI) techniques, including monitoring tumor growth and investigating intracellular signaling activity in vitro and in vivo. Cell permeable. Emission maximum = 562 nm.
D-Luciferin sodium salt

storage

-20°C

Properties of D-Luciferin sodium salt

storage temp.  -20°C
solubility  H2O: soluble
form  lyophilized powder
color  Yellow
InChI InChI=1/C11H8N2O3S2.Na.H/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;;/h1-3,7,14H,4H2,(H,15,16);;/t7-;;/s3
CAS DataBase Reference 103404-75-7(CAS DataBase Reference)

Safety information for D-Luciferin sodium salt

Computed Descriptors for D-Luciferin sodium salt

InChIKey ZONJDNKUJJUQCK-DCFBZVEJNA-N
SMILES C([C@H]1CSC(C2=NC3C=CC(O)=CC=3S2)=N1)(=O)O.[NaH] |&1:1,r|

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