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HomeProduct name listD-Histidine

D-Histidine

Synonym(s):(R)-2-Amino-3-(4-imidazolyl)propionic acid;D-α-Amino-β-(4-imidazolyl)propionic acid

  • CAS NO.:351-50-8
  • Empirical Formula: C6H9N3O2
  • Molecular Weight: 155.15
  • MDL number: MFCD00065963
  • EINECS: 206-513-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
D-Histidine Structural

What is D-Histidine?

Chemical properties

white crystalline powder

The Uses of D-Histidine

D-Histidine is the unnatural, biologically inactive isomer of L-Histidine (H456010). D-histidine is known to inhibit cell division, and is also used by certain types of bacteria (such as Escherichia coli) as a source of L-Histidine.

What are the applications of Application

D-Histidine is an essential amino acid inactive isomer

Definition

ChEBI: An optically active form of histidine having D-configuration.

Biochem/physiol Actions

D-Histidine may be used in the design of peptide drugs, cationic peptides, such as analogues of carnosine. D-Histidine may also be used as a heavy metal sequestration agent.

Properties of D-Histidine

Melting point: 280 °C
alpha  -12 º (c=11, 6N HCl)
Boiling point: 278.95°C (rough estimate)
Density  1.3092 (rough estimate)
refractive index  -13 ° (C=11, 6mol/L HCl)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  1 M HCl: soluble
form  Free-Flowing Powder
pka 1.91±0.10(Predicted)
color  White
Water Solubility  42 g/L (25 ºC)
Merck  14,4720
BRN  84089
Stability: Hygroscopic
CAS DataBase Reference 351-50-8(CAS DataBase Reference)
EPA Substance Registry System D-Histidine (351-50-8)

Safety information for D-Histidine

Signal word Warning
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P310:Immediately call a POISON CENTER or doctor/physician.
P363:Wash contaminated clothing before reuse.
P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P233:Store in a well-ventilated place. Keep container tightly closed.

Computed Descriptors for D-Histidine

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