D-Histidine
Synonym(s):(R)-2-Amino-3-(4-imidazolyl)propionic acid;D -α-Amino-β-(4-imidazolyl)propionic acid
- CAS NO.：351-50-8
- Empirical Formula: C6H9N3O2
- Molecular Weight: 155.15
- MDL number: MFCD00065963
- EINECS: 206-513-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-30 16:33:02
What is D-Histidine?
Chemical properties
white crystalline powder
The Uses of D-Histidine
D-Histidine is the unnatural, biologically inactive isomer of L-Histidine (H456010). D-histidine is known to inhibit cell division, and is also used by certain types of bacteria (such as Escherichia coli) as a source of L-Histidine.
What are the applications of Application
D-Histidine is an essential amino acid inactive isomer
Definition
ChEBI: An optically active form of histidine having D-configuration.
Biochem/physiol Actions
D-Histidine may be used in the design of peptide drugs, cationic peptides, such as analogues of carnosine. D-Histidine may also be used as a heavy metal sequestration agent.
Properties of D-Histidine
| Melting point: | 280 °C |
| alpha | -12 º (c=11, 6N HCl) |
| Boiling point: | 278.95°C (rough estimate) |
| Density | 1.3092 (rough estimate) |
| refractive index | -13 ° (C=11, 6mol/L HCl) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 1 M HCl: soluble |
| form | Free-Flowing Powder |
| pka | 1.91±0.10(Predicted) |
| color | White |
| Water Solubility | 42 g/L (25 ºC) |
| Merck | 14,4720 |
| BRN | 84089 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 351-50-8(CAS DataBase Reference) |
| EPA Substance Registry System | D-Histidine (351-50-8) |
Safety information for D-Histidine
| Signal word | Warning |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P363:Wash contaminated clothing before reuse. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for D-Histidine
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