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HomeProduct name listCZC24832

CZC24832

Synonym(s):5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridinesulfonamide;5-(2-Amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide;CZC-24832

  • CAS NO.:1159824-67-5
  • Empirical Formula: C15H17FN6O2S
  • Molecular Weight: 364.4
  • MDL number: MFCD22417090
  • EINECS: 200-258-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-02 08:55:16
CZC24832 Structural

What is CZC24832?

The Uses of CZC24832

CZC24832 is a selective phosphoinositide 3-kinase γ (PI3Kγ) inhibitor. CZC24832 regulates interleukin-17-producing T helper cell (TH17) differentiation by PI3Kγ thus making CZC24832 a potential treatment for inflammatory and autoimmune diseases.

Properties of CZC24832

Density  1.51
storage temp.  Store at -20°C
solubility  insoluble in H2O; insoluble in EtOH; ≥6.07 mg/mL in DMSO with gentle warming
form  solid
pka 10.29±0.50(Predicted)
color  White to off-white

Safety information for CZC24832

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for CZC24832

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