Cyproconazole

Chemical properties

Colorless, crystalline solid. Odorless.

The Uses of Cyproconazole

Cyproconazole is a fungicide treatment for wood preservative that prevents decay from fungi in above-ground applications.

The Uses of Cyproconazole

Cyproconazole is used to inhibit demeythylation in fungal sterol synthesis. And it is used on greenhouse and field-grown roses and as a wood preservative, surface application or pressure treatment of wood for above-ground uses, including siding, plywood, millwork, shingles, lumber.

The Uses of Cyproconazole

Cyproconazole is used as a systemic fungicide to control cereal and sugar beet foliar diseases: Septoria, rust, powdery mildew, Rhyncosporium, Cercospora and Ramularia. It is also used in fruit trees, vines, coffee, banana, turf, and vegetables to control Venturia, powdery mildew, rust, Mycosphaerela, Monilia, Mycena, Sclerotinia and Rhizoctonia.

What are the applications of Application

Cyproconazole is a triazole fungicide

Definition

ChEBI: 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol is a tertiary alcohol that is butan-2-ol substituted by a 4-chlorophenyl group at position 2, a cyclopropyl group at position 3 and a 1H-1,2,4-triazol-1-yl group at position 1. It is a member of monochlorobenzenes, a tertiary alcohol, a member of triazoles and a member of cyclopropanes.

Agricultural Uses

Fungicide: Used to control fungus on cereals, coffee beans; anthracnose and other diseases on turfgrass; used against rust and leaf spot disease.

Trade name

ALTO®; ALTO®, ELITE; ATEMI®; ATEMI-50-SL®;EVIPOL®; FLINT®; NOAH GOLD®; SAN-619 F®; SENTINEL®; SN 108266®

Potential Exposure

Triazole fungicide used to control fun- gus on cereals, coffee beans; anthracnose and other diseases on turfgrass; used against rust and leaf spot disease.

Metabolic pathway

Cyproconazole is a mixture of diastereiosomers and the preferential mammalian metabolism of one isomer has been observed. Pathways of metabolism in plants and mammals are quite similar. Metabolism primarily involves oxidation of the terminal methyl group to alcohols and carboxylic acids and/or hydroxylation at the 3-position. Loss of the alkyl cyclopropyl moiety or the triazolyl ring also occurs.

Shipping

UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz- ardous material, Technical Name Required

Degradation

Cyproconazole is stable and decomposition was <5% after 2 years. It was stable in aqueous solutions (at pH 1-9) for 35 days (50 °C) or 14 days (80 °C). It is slowly hydrolysed in hydrochloric acid or sodium hydroxide.
¹⁴C-Labelled cyproconazole was applied at a rate equivalent to 100 g ha^-1 to the surface of a 2 mm layer of loam soil. The samples were exposed to natural sunlight for up to 72 days on open dishes or in flasks fitted with plugs to trap volatile products. Samples were extracted at intervals and analysed. After 37 days exposure on dishes, 50% of the applied cyproconazole remained whereas 85% remained after 72 days in the flasks. In the dishes, unextractable residues amounted to 13-20% of the applied radiolabel after 20 days or more exposure, whereas in the flasks it reached a maximum of 6% after 15 days. The products identified in the dishes were: 1-(4-chlorophenyl)-2-(1H -1,2,4-triazol-l-yl)- ethanone (2, 5%), 3-cyclopropyl^-1-(1H-1,2,4-triazol-l-yl)butanone(4,4%), 2-(2- or 3-hydroxy-4-chlorophenyl)-3-cyclopropyl-1-(1H -1,2,4-triazol^-1-yl)- butan-2-ol (3 4%), and 4-chlorobenzoic acid 5 (Scheme 1) (PSD, 1991). Degradation in the flasks was similar but occurred to a lesser extent. No volatde products were trapped and recoveries of radiolabel were 94- 102%.

Incompatibilities

The triazoles are sensitive to heat, fric- tion, and impact. Sensitivity varies with the type substitu- tion to the triazole ring. Metal chelated and halogen substitution of the triazol ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives .

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Contact a licensed disposal facility about surplus and nonrecyclable solutions. Burn in a chemical incinerator equipped with an afterburner and scrubber. Extra care must be exercised as the material in an organic solvent is highly flammable. In accordance with 40CFR165, follow recom- mendations for the disposal of pesticides and pesticide con- tainers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by con- tacting your regional EPA office. Incineration or permanga- nate oxidation.