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CTAP

CTAP Structural

What is CTAP?

The Uses of CTAP

CTAP acts as a selective μ-opioid receptor antagonist with a multitude of applications including the regulation of aggressive behavior in mammals. Activation of μ-opioid receptors in the central nucleus of the amygdala, is responsible for mechanisms related to the control of sodium appetite and regulation of sodium intake.

The Uses of CTAP

CTAP has been used as a μ-opioid receptor (MOR) antagonist:

  • to study the anti-hyperalgesic effect of dipeptidyl peptidase 4 (DPP4) inhibitor isoleucine-proline-isoleucine (IPI) and vildagliptin in carrageenan-induced inflammation
  • to study the role of MOR in glutamate and gamma-aminobutyric acid (GABA) efflux during predator stress in rats
  • to determine the endogenous opioid peptide involved in blocking pain induced by activated gastrin-releasing peptide (Grp+) neurons

Biochem/physiol Actions

CTAP is a peptide antagonist produced from somatostatin analogs.

storage

Store at -20°C

Properties of CTAP

storage temp.  -20°C
form  Solid
Water Solubility  Soluble to 1 mg/ml in water

Safety information for CTAP

Computed Descriptors for CTAP

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