Collagen

The Uses of Collagen

collagen (soluble) demonstrates enhanced moisture uptake and, therefore, is more effective than collagen. This is a clear liquid form of collagen preferred for use in cosmetics because, when incorporated into a formulation, it does not separate as regular collagen can. When incorporated into detergents, soluble collagen significantly reduces the amount of amino acids extracted from the skin when washing with the detergents and water. Soluble collagen is perhaps the most widely used and recognized high molecularweight protein in skin care formulations.

The Uses of Collagen

collagen is very popular in skin care formulations for its strong hydration potential and its ability to bind and retain many times its weight in water. This water-binding and retention ability makes collagen effective for use in skin moisturizers as a skin-protecting agent. It will not leave a feeling of tackiness or dryness on the skin, especially when used in hydrolyzed or soluble forms. As a film former, collagen aids in reducing natural moisture loss, thereby helping hydrate the skin. In skin care preparations, it enhances the humectancy of a topical product, contributes sheen, builds viscosity, and leaves the skin smooth and soft. It is not water soluble, and has been very popular in cosmetic formulations for more than 30 years. Collagen is rich in proline and hydroxyproline, and is considered a “commercially pure” protein. originally derived from animal connective tissue, which is similar to the collagen produced by the body in the skin and bones, today for cosmetic use it is either synthetically derived or bioengineered. Also considered an anti-irritant, collagen does not cause allergic reactions when used on the skin. It is very stable, bland in odor, and light in color. This is one of the most effective and economical proteins available to cosmetic formulators.

The Uses of Collagen

Collagen is a protein that is the principal constituent of connective tissue and bones of vertebrates; it can be converted to gelatin and glue by boiling in water.

Definition

collagen: An insoluble fibrous proteinfound extensively in the connectivetissue of skin, tendons, andbone. The polypeptide chains of collagen(containing the amino acidsglycine and proline predominantly)form triple-stranded helical coils that are bound together to form fibrils,which have great strength and limitedelasticity. Collagen accounts forover 30% of the total body protein ofmammals.

General Description

Collagen solution is derived by dissolving collagen molecules in an aqueous solution. Collagen type Iα1 (COL1A1) is encoded by the gene that is located on human chromosome 17q21.33. It is the most abundant extracellular matrix (ECM) protein in humans. Type 1 collagen is the major structural protein of bone, tendon, skin and cornea. The encoded protein is a heterotrimer consisting of two α1-chains and one α2-chain.

Agricultural Uses

Collagen is an insoluble fibrous protein found extensively in the connective tissue of skin, tendons and bones. Polypeptide chains of collagen predominantly contain glycine and proline. These form triple-stranded, helical coils to form fibrils, which have strength and elasticity. Collagen accounts for over 30% of the total body protein in mammals.

Biochem/physiol Actions

Collagen provides extracellular support for multicellular animals. Collagen type I offers mechanical stability, strength and toughness to a range of tissues from tendons and ligaments, to skin, cornea, bone and dentin.