Chloromethyl chlorosulfate

CAS NO.：49715-04-0
Empirical Formula: CH2Cl2O3S
Molecular Weight: 165
MDL number: MFCD00041547
EINECS: 256-442-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-07-04 17:14:15

What is Chloromethyl chlorosulfate?

Chemical properties

Clear colourless to yellow liquid

The Uses of Chloromethyl chlorosulfate

Reagent for chloromethylation of Fmoc-protected amino acids without the generation of carcinogenic bis(chloromethyl)ether.

What are the applications of Application

Chloromethyl chlorosulfate is a reagent for chloromethylation of Fmoc-protected amino acids without the generation of carcinogenic bis(chloromethyl)ether.

Properties of Chloromethyl chlorosulfate

Boiling point:	45-50 °C/10 mmHg
Density	1.631 g/mL at 25 °C
refractive index	n 20/D 1.448
Flash point:	176 °F
storage temp.	2-8°C
solubility	soluble in Chloroform, Ethyl Acetate
form	Liquid
color	Clear colorless to yellow
Water Solubility	reacts
Stability:	Moisture Sensitive
CAS DataBase Reference	49715-04-0(CAS DataBase Reference)

Safety information for Chloromethyl chlorosulfate

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H314:Skin corrosion/irritation H330:Acute toxicity,inhalation H350:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.