CHARTREUSIN

CAS NO.：6377-18-0
Empirical Formula: C32H32O14
Molecular Weight: 640.59
MDL number: MFCD00467138
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is CHARTREUSIN?

The Uses of CHARTREUSIN

Chartreusin is an antitumour antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II.

The Uses of CHARTREUSIN

Chartreusin is an antitumor antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II.

The Uses of CHARTREUSIN

Chartreusin is an antiproliferative agent that inhibits topoisomerase II.

What are the applications of Application

Chartreusin is an antiproliferative agent that inhibits topoisomerase II

Definition

ChEBI: Chartreusin is a glycoside and a benzochromenone.

Properties of CHARTREUSIN

Melting point:	185℃
Boiling point:	592.39°C (rough estimate)
alpha	D25 +132.5° (c = 0.2 in pyridine); D25 -33° (c = 0.3 in glacial acetic acid)
Density	1.3027 (rough estimate)
refractive index	1.6130 (estimate)
storage temp.	2-8°C
solubility	Chloroform (Slightly, Heated), Methanol (Slightly), Pyridine (Slightly)
form	Yellow solid.
pka	6?+-.0.20(Predicted)
color	Light Yellow to Yellow
Water Solubility	15mg/L(25 ºC)
Stability:	Hygroscopic