Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listCefcapene pivoxil

Cefcapene pivoxil

  • CAS NO.:105889-45-0
  • Empirical Formula: C23H29N5O8S2
  • Molecular Weight: 567.64
  • MDL number: MFCD00870176
  • EINECS: 1806241-263-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
Cefcapene pivoxil Structural

What is Cefcapene pivoxil?

Description

Flomox was launched in Japan as an orally active cephalosporin for respiratory and urinary tract infections, heptatic infections, ophthalmological and otorhinolarynological infections, skinkoft tissue infections, and for use in gynacology, dentistry and oral surgery. It can be prepared by condesation of 2(Z)-(2-(t-butoxycarbonylamino) thiazol-4-yl)-2-pentenoic acid with 7-amino-3-(carbanoyloxymethyl)- 3-cephem-4-carboxylic acid pivaloyl methyl ester followed by deprotection. Flomox is highly active against a wide variety of Gram-positive and Gram-negative bacteria, except for several strains such as Pseudomonas aeruginosa and enterococci, by acting as a cell wall synthesis inhibitor (β-lactamase stability against TEM-1 type β-lactamases) and is more effective than cefaclor and cefdinir. Absorption is improved by the pivaloyloxymethyl ester group which is easily lost by deesterification during GI absorption to produce the biologically active form. The pivalic acid generated quickly conjugates with carnitine and is excreted in the urine. The drop in plasma levels of carnitine was dose dependent and returned to normal levels upon termination of treatment.

Chemical properties

Off-White Solid

Originator

Shionogi (Japan)

The Uses of Cefcapene pivoxil

Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, cefcapene

The Uses of Cefcapene pivoxil

Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, Cefcapene.

What are the applications of Application

Cefcapene Pivoxil is Antibacterial and ester prodrug of cefcapene

brand name

Flomox

Properties of Cefcapene pivoxil

Melting point: 158-164°C
Boiling point: 888.4±65.0 °C(Predicted)
Density  1.47±0.1 g/cm3(Predicted)
solubility  DMSO, Water( warm)
form  Solid
pka 11.33±0.60(Predicted)
color  Off-White

Safety information for Cefcapene pivoxil

Computed Descriptors for Cefcapene pivoxil

Related products of tetrahydrofuran

You may like

  • 105889-45-0 Cefcapene Piroxil 99%
    105889-45-0 Cefcapene Piroxil 99%
    105889-45-0
    View Details
  • 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    99903-60-3
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.