CANNABINOL

CAS NO.：521-35-7
Empirical Formula: C21H26O2
Molecular Weight: 310.43
MDL number: MFCD00056774
EINECS: 689-788-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-03-27 16:59:26

What is CANNABINOL?

Chemical properties

thin platelets

The Uses of CANNABINOL

A metabolite of Tetrahydrocannabinol (T293200). A psychoactive substance cannabinoid that acts as a weak agonist of the CB1 and CB2 receptors.

Definition

ChEBI: Cannabinol is a dibenzopyran.

General Description

Leaflets.

Reactivity Profile

CANNABINOL is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

Flash point data for CANNABINOL are not available, but CANNABINOL is probably combustible.

Biological Activity

CB 1 and CB 1 receptor agonist (K i values are 126 and 211 nM respectively). Inhibits adenylyl cyclase (EC 50 values are 120 and 261 nM for CB 1 and CB 2 receptors respectively) and suppresses immune cell function. Major constituent of cannabis; displays little or no psychotropic activity.

Purification Methods

Cannabinol crystallises from pet ether and sublimes in a vacuum. [Meitzer et al. Synthesis 985 1981, Beilstein 17 II 151, 17 III/IV 1652.]

Properties of CANNABINOL

Melting point:	76-77°
Boiling point:	bp0.05 185°
Density	1.0865 (rough estimate)
refractive index	1.4900 (estimate)
Flash point:	11 °C
storage temp.	2-8°C
pka	9.40±0.40(Predicted)
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
EPA Substance Registry System	Cannabinol (521-35-7)

Safety information for CANNABINOL

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H225:Flammable liquids H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.