Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listBUTEIN

BUTEIN

Synonym(s):2ʹ,4ʹ,3,4-Tetrahydroxychalcone;Butein - CAS 487-52-5 - Calbiochem

  • CAS NO.:487-52-5
  • Empirical Formula: C15H12O5
  • Molecular Weight: 272.25
  • MDL number: MFCD00017300
  • EINECS: 207-659-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-09-04 15:51:00
BUTEIN Structural

What is BUTEIN?

Chemical properties

Yellow Solid

The Uses of BUTEIN

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent

What are the applications of Application

Butein is inhibits the tyrosine kinase activity of the EGF receptor and p60c-src

Definition

ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.

General Description

Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood of?Dalbergia odorifera, Caragana jubata and?Rhus verniciflua?stokes, and the stem bark of cashews (Semecarpus anacardium).

Biochem/physiol Actions

Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells.

Properties of BUTEIN

Melting point: 216°C
Boiling point: 560.9±50.0 °C(Predicted)
Density  1.483±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: >50 mg/mL
form  solid
pka 7.44±0.35(Predicted)
color  yellow
CAS DataBase Reference 487-52-5(CAS DataBase Reference)

Safety information for BUTEIN

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for BUTEIN

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.