Bupranolol
- CAS NO.：14556-46-8
- Empirical Formula: C14H22ClNO2
- Molecular Weight: 271.78
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Bupranolol?
Originator
Betadrenol,Pharma-Schwarz,W. Germany,1969
The Uses of Bupranolol
Bupranolol is an antagonist at the cardiostimulatory low-affinity state of b(1)-adrenoceptors and is known to treat hypertension and tachycardia.
Definition
ChEBI: Bupranolol is an aromatic ether.
Manufacturing Process
A mixture of 16.3 g of (2-chloro-5-methylphenyl)glycidic ether (from epichlorohydrin and 2-chloro-5-methylphenol) and 6.2 g of t-butylamine in 50 ml of ethanol is heated at reflux for 6 hours. The solvent is removed, the residue is washed with water and then extracted with benzene. The dried extract is evaporated to give 1-t-butylamino-3-(2-chloro-5-methylphenoxy)-2- propanol. Treatment of the free base in benzene solution with dry hydrogen chloride yields the hydrochloride salt.
Therapeutic Function
Antiarrhythmic
Properties of Bupranolol
| Melting point: | 71-74°C |
| Boiling point: | 396.3±42.0 °C(Predicted) |
| Density | 1.098±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, Refrigerator, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.82±0.20(Predicted) |
| color | White to Off-White |
Safety information for Bupranolol
Computed Descriptors for Bupranolol
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![[3-(2-CHLORO-PHENOXY)-PROPYL]-METHYL-AMINE](https://img.chemicalbook.in/CAS/GIF/883547-84-0.gif)
![3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride](https://img.chemicalbook.in/CAS/GIF/15148-80-8.gif)
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