BRUSATOL
Synonym(s):(+)-Brusatol;(11β,12α,15β)-13,20-Epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-picras-3-en-21-oic acid methyl ester;Brutasol;NSC 172924;Yatansin
- CAS NO.:114420-67-6
- Empirical Formula: C20H26O11
- Molecular Weight: 442.41
- MDL number: MFCD32263358
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is BRUSATOL?
The Uses of BRUSATOL
Clinically, the research shows brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism, and it provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity. Brusatol overcomes chemoresistance through inhibition of protein translation.
Properties of BRUSATOL
Boiling point: | 727.5±60.0 °C(Predicted) |
Density | 1.46±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
form | Solid |
pka | 8.58±0.15(Predicted) |
color | White to off-white |
CAS DataBase Reference | 114420-67-6 |
Safety information for BRUSATOL
Computed Descriptors for BRUSATOL
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 6-Bromo-3-iodo-1-methyl-1H-indazole N-octanoyl benzotriazole 3,4-Dibenzyloxybenzaldehyde 4-Hydrazinobenzoic acid Electrolytic Iron Powder 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 4-HYDROXY BENZYL ALCOHOL 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) S-2-CHLORO PROPIONIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine N-Boc-L-proline methyl ester 2-(BOC-Amino)4-picoline 1-(4-Methylphenylsulfonyl)-1H-1,2,3-benzotriazole 1-(2-Chlorobenzyl)-4-nitro-1H-pyrazoleRelated products of tetrahydrofuran
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Menadione
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