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HomeProduct name listBRUSATOL

BRUSATOL

Synonym(s):(+)-Brusatol;(11β,12α,15β)-13,20-Epoxy-3,11,12-trihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-picras-3-en-21-oic acid methyl ester;Brutasol;NSC 172924;Yatansin

BRUSATOL Structural

What is BRUSATOL?

The Uses of BRUSATOL

Clinically, the research shows brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism, and it provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity. Brusatol overcomes chemoresistance through inhibition of protein translation.

Properties of BRUSATOL

Boiling point: 727.5±60.0 °C(Predicted)
Density  1.46±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
form  Solid
pka 8.58±0.15(Predicted)
color  White to off-white
CAS DataBase Reference 114420-67-6

Safety information for BRUSATOL

Computed Descriptors for BRUSATOL

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