BroMosporine
- CAS NO.：1619994-69-2
- Empirical Formula: C17H20N6O4S
- Molecular Weight: 404.44
- MDL number: MFCD26142669
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-04 15:51:00
What is BroMosporine?
Description
Bromosporine (1619994-69-2) is a potent pan-Bromodomain (BRD) inhibitor.1?Bromosporine was able to reactivate HIV-1 replication in different latency models.2
The Uses of BroMosporine
Bromosporine is a broad spectrum inhibitor for bromodomains.
storage
Store at +4°C
References
1) Picaud?et al.?(2016),?Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia; Sci. Adv.?2?e1600760 2) Pan?et al.?(2017),?The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells; Oncotarget?8?94104
Properties of BroMosporine
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in DMSO (up to 25 mg/ml) |
| form | solid |
| pka | 6.21±0.46(Predicted) |
| color | Off-white |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Safety information for BroMosporine
Computed Descriptors for BroMosporine
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