Bromomethyl methyl ether

CAS NO.：13057-17-5
Empirical Formula: C2H5BrO
Molecular Weight: 124.96
MDL number: MFCD00000171
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:22

What is Bromomethyl methyl ether?

Chemical properties

Colorless liquid

The Uses of Bromomethyl methyl ether

Bromomethyl methyl ether is used as reagent for protection of OH groups as their methoxymethyl (MOM) ethers. It is used in enantiocontrolled synthesis of intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506. It was used in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone.

The Uses of Bromomethyl methyl ether

Bromomethyl methyl ether was used in enantiocontrolled synthesis of intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506. It was used in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone.

Properties of Bromomethyl methyl ether

Boiling point:	87 °C (lit.)
Density	1.531 g/mL at 25 °C (lit.)
refractive index	n20/D 1.456(lit.)
Flash point:	80 °F
storage temp.	2-8°C
solubility	Chloroform (Soluble), Methanol (Slightly)
form	clear liquid
color	Colorless to Light yellow to Light orange
Specific Gravity	1.531
Water Solubility	Sparingly soluble in water.
Sensitive	Moisture Sensitive
BRN	1730853
CAS DataBase Reference	13057-17-5(CAS DataBase Reference)
NIST Chemistry Reference	Bromomethyl methyl ether(13057-17-5)
EPA Substance Registry System	Methane, bromomethoxy- (13057-17-5)

Safety information for Bromomethyl methyl ether

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention.