Bromo-PEG4-acid
- CAS NO.：1393330-38-5
- Empirical Formula: C11H21BrO6
- Molecular Weight: 329.18
- MDL number: MFCD22574799
- Update Date: 2024-10-23 13:36:13
What is Bromo-PEG4-acid?
Description
Bromo-PEG4-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Properties of Bromo-PEG4-acid
| Boiling point: | 426.9±40.0 °C(Predicted) |
| Density | 1.352±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| pka | 4.28±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Bromo-PEG4-acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Bromo-PEG4-acid
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