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HomeProduct name listBromazine Hydrochloride

Bromazine Hydrochloride

Synonym(s):Bromodiphenhydramine hydrochloride;Diphenhydramine impurity C (PhEur);2-[(RS)-(4-Bromophenyl)phenylmethoxy]-N,N-dimethylethanamine hydrochloride;2-[(4-Bromophenyl)phenylmethoxy]ethyl(dimethyl)ammonium chloride;2-[(RS)-(4-BROMOPHENYL) PHENYLMETHOXY]-N,NDIMETHYLETHANAMINE HYDROCHLORIDE

  • CAS NO.:1808-12-4
  • Empirical Formula: C17H21BrClNO
  • Molecular Weight: 370.71174
  • MDL number: MFCD01727165
  • EINECS: 2173109
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-07 21:39:59
Bromazine Hydrochloride Structural

What is Bromazine Hydrochloride?

Description

Bromodiphenhydramine is a histamine H1 receptor antagonist. It induces histamine release in isolated guinea pig lung when used at a concentration of 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs when used at concentrations of 100 and 200 μg/ml. Bromodiphenhydramine (17 mg/kg) inhibits formalin-induced paw edema in rats. It increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg.

The Uses of Bromazine Hydrochloride

Antihistaminic.

Definition

ChEBI: The hydrochloride salt of bromazine. An antihistamine with antimicrobial properties, it is used in the control of cutaneous allergies.

brand name

Ambodryl.

General Description

Bromodiphenhydraminehydrochloride, 2-[(4-bromophenyl)-phenylmethoxy]-N, N-dimethylethanamine hydrochloride(Ambodryl Hydrochloride), is a white to pale buff crystallinepowder that is freely soluble in water and in alcohol.Relative to diphenhydramine, bromodiphenhydramine ismore lipid soluble and was twice as effective in protectingagainst the lethal effects of histamine aerosols.

Properties of Bromazine Hydrochloride

Melting point: 144-145°
storage temp.  Refrigerator
solubility  Acetone (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
color  Pale Yellow
BRN  3754363

Safety information for Bromazine Hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral

Computed Descriptors for Bromazine Hydrochloride

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