Bromadiolone
Synonym(s):Bromodiolone
- CAS NO.:28772-56-7
- Empirical Formula: C30H23BrO4
- Molecular Weight: 527.41
- MDL number: MFCD00128053
- EINECS: 249-205-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-14 15:18:26
What is Bromadiolone?
Description
Bromadiolone is used to control rodents around buildings, inside transport vehicles and sewers. It is often formulated as meal bait, rat and mouse bait ready-to-use place packs, paraffinized pellets and blocks.
Chemical properties
Bromadiolone is white to off-white (yellowish) powder.
Occurrence
Boldo is an evergreen found in Chile, Peru, and Morocco.
The Uses of Bromadiolone
Bromadiolone is an anticoagulant rodenticide used on non-crop areas.
The Uses of Bromadiolone
Rodenticide.
The Uses of Bromadiolone
Bromadiolone is used for the control of rats and mice.
What are the applications of Application
Bromadiolon is an anticoagulant
Definition
ChEBI: Bromadiolone is a diarylheptanoid.
General Description
Yellowish powder. Used as an anticoagulant rodenticide.
Health Hazard
The compound is toxic by oral exposure.
Fire Hazard
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated to decomposition, Bromadiolone emits toxic fumes of bromine containing compounds.
Agricultural Uses
Rodenticide: Bromadiolone is used as an anticoagulant rodenticide and used as bait for rodent control against house mice, roof rats and warfarin-resistant Norway rats. It is also authorized by USDA for use in official establishments operating under the Federal meat, poultry, shell egg grading and egg products inspection program.
Trade name
BOLDO®; BOOT HILL®; BROMONE®; CANADIEN 2000®; CONTRAC®; HAWK®; LM- 637®; MAKI®; RAT ARREST®; RAT FREE®; RATIMUS®; RENTOKIL DEADLINE®; SLAYMOR®; SUPER-CAID®; SUPER-ROZOL®; SUP'ORATS®; TERMUS®
Potential Exposure
Bromadiolone is used as an anticoagulant rodenticide. It is bait for rodent control used against house mice, roof rats, warfarin-resistant Norway rats. It is also authorized by USDA for use in official establishments operating under the federal meat, poultry, shell egg grading, and egg products inspection program. May be used as a drug.
First aid
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit. Keepvictim quiet and maintain normal body temperature. Effectsmay be delayed; keep victim under observation.
Environmental Fate
Bromadiolone belongs to second generation of long-acting anticoagulant rodenticide. It acts by interfering with the prothrombin synthesis by blocking the regeneration of vitamin K dependant proteins in the liver and thereby disrupting the clotting mechanisms and increasing the tendency to hemorrhages and subsequent death.
Metabolic pathway
Metabolism in the rat is very slow and products other than a conjugate of the parent compound have not been identified. Biodegradation in soil and plants has not been reported.
storage
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with bromadiolone you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area.
Shipping
UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1—Poisonous materials. UN3026 Coumarin derivative pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1—Poisonous materials.
Degradation
Bromadiolone is a stable compound. It is a weak acid.
Toxicity evaluation
Bromadiolone may be released into the environment
through various waste streams and its use.
If released to air, it will exist in the particulate phase in the
ambient atmosphere and will be removed by dry and wet deposition. In soil, it is not persistent under aerobic conditions
(half-life is 14 days) and is usually immobile except in soils of
low organic matter and clay, such as sand.
When released to water, it adsorbs to suspended solids
and sediment. Bromadiolone is stable to hydrolysis at pH 5,
7, and 9. Two major degradates, [1,3-diphenyl-5(40-bromobiphenyl)
pentane-1-ol] and [1,3-diphenyl-5(40-bromobiphenyl)
pentane-1,5-diol], are detected in the aerobic soil
metabolism study.
Bromadiolone is bioaccumulated in edible and nonedible
tissues in bluegill sunfish at the bioaccumulation concentration
factors of 160X and 1658X. It was also detected in birds.
Properties of Bromadiolone
Melting point: | 200-210° |
Boiling point: | 723.4±60.0 °C(Predicted) |
Density | 1.3243 (rough estimate) |
vapor pressure | 2 x l0-6Pa (20 °C) |
refractive index | 1.4490 (estimate) |
storage temp. | -20°C |
solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml |
form | Powder |
Water Solubility | 19 mg l-1 (20 °C) |
pka | 4.04(at 21℃) |
Merck | 13,1366 |
BRN | 1335336 |
CAS DataBase Reference | 28772-56-7(CAS DataBase Reference) |
EPA Substance Registry System | Bromadiolone (28772-56-7) |
Safety information for Bromadiolone
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09 |
GHS Hazard Statements |
H372:Specific target organ toxicity, repeated exposure H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Bromadiolone
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
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