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HomeProduct name listBIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE

BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE

Synonym(s):Chlorobis(N,N-diisopropyl)phosphoramidite;Chlorobis(N,N-diisopropylamino)phosphine;Tetraisopropylphosphorodiamidous chloride

BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE Structural

What is BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE?

Description

Bis(diisopropylamino)chlorophosphine is a white to off-white powder to crystalline organophosphorus compound, mainly used as an organic synthetic raw material or reaction reagent. It can be used in the synthesis of mixed phosphorothioate and methylenephosphine derivatives, etc. It is commonly used in chemical production and laboratory research.

Chemical properties

white to light yellow crystal powde

The Uses of BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE

Bis(diisopropylamino)chlorophosphine has been used in the synthesis of tert-butyl tetraisopropylphosphorodiamidite ligand for palladium-catalyzed Buchwald–Hartwig amination reaction.

It is also can be used to synthesize:

  • acyclic N-phosphonio imine catalyst for selective epoxidations
  • boryl-substituted methylenephosphonium derivatives

What are the applications of Application

Bis(diisopropylamino)chlorophosphine is a compound containing various amounts of diisopropylamine hydrochloride

Properties of BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE

Melting point: 100-104 °C(lit.)
Boiling point: 291℃
Flash point: 130℃
storage temp.  Store under inert gas
pka 4.50±0.70(Predicted)
form  Powder
color  white to off-white
Sensitive  air sensitive, moisture sensitive
CAS DataBase Reference 56183-63-2(CAS DataBase Reference)

Safety information for BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE

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