BIBF 1202
- CAS NO.：894783-71-2
- Empirical Formula: C30H31N5O4
- Molecular Weight: 525.6
- MDL number: MFCD28167767
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is BIBF 1202?
Description
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
The Uses of BIBF 1202
Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.
Properties of BIBF 1202
| Melting point: | >216°C (dec.) |
| Boiling point: | 759.5±60.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Aqueous Base (Slightly, Heated) |
| form | Solid |
| pka | 3.94±0.20(Predicted) |
| color | Light Yellow to Yellow |
Safety information for BIBF 1202
Computed Descriptors for BIBF 1202
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate](https://img.chemicalbook.in/CAS/GIF/1160293-27-5.gif)
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