BIBF 1202
- CAS NO.：894783-71-2
- Empirical Formula: C30H31N5O4
- Molecular Weight: 525.6
- MDL number: MFCD28167767
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is BIBF 1202?
Description
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
The Uses of BIBF 1202
Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.
Properties of BIBF 1202
| Melting point: | >216°C (dec.) |
| Boiling point: | 759.5±60.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Aqueous Base (Slightly, Heated) |
| form | Solid |
| pka | 3.94±0.20(Predicted) |
| color | Light Yellow to Yellow |
Safety information for BIBF 1202
Computed Descriptors for BIBF 1202
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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