BIBF 1202
- CAS NO.:894783-71-2
- Empirical Formula: C30H31N5O4
- Molecular Weight: 525.6
- MDL number: MFCD28167767
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:15
What is BIBF 1202?
Description
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
The Uses of BIBF 1202
Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.
Properties of BIBF 1202
Melting point: | >216°C (dec.) |
Boiling point: | 759.5±60.0 °C(Predicted) |
Density | 1.331±0.06 g/cm3(Predicted) |
storage temp. | Refrigerator |
solubility | Aqueous Base (Slightly, Heated) |
form | Solid |
pka | 3.94±0.20(Predicted) |
color | Light Yellow to Yellow |
Safety information for BIBF 1202
Computed Descriptors for BIBF 1202
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 2,2-diethoxyethanethioamide Tubulysin D Tubulysin F Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(4-Bromopyridin-2-yl)acetonitrile 4-Bromo-N,N-bis(4-iodophenyl)aniline 2-(2,4-Dibutoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester 3-Morpholino-5,6-dihydropyridin-2(1H)-one 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucito 4,6-difluoro-1H-indole (±)-1-Phenylethane ethane sulfonic acid ert-butyl 3-[(prop-2-yn-1-yl)amino]propanoateRelated products of tetrahydrofuran
1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate
Methyl oxindole-5-carboxylate
P-ANISALDEHYDE DIMETHYL ACETAL
Nintedanib Impurity 15
Methyl 1-acetyl-2-oxoindoline-6-carboxylate
(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER
N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
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