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HomeProduct name listMethyl 1-acetyl-2-oxoindoline-6-carboxylate

Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Methyl 1-acetyl-2-oxoindoline-6-carboxylate Structural

What is Methyl 1-acetyl-2-oxoindoline-6-carboxylate?

The Uses of Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Properties of Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Boiling point: 489.5±45.0 °C(Predicted)
Density  1.330
solubility  DMSO (Slightly), Methanol (Slightly)
pka -1.94±0.20(Predicted)
form  Solid
color  Off-White to Pale Red

Safety information for Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Methyl 1-acetyl-2-oxoindoline-6-carboxylate

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