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HomeProduct name listBetamethasone 21-phosphate disodium

Betamethasone 21-phosphate disodium

Synonym(s):Betamethasone 21-phosphate disodium;Betamethasone disodium phosphate;Betamethasone sodium phosphate

  • CAS NO.:151-73-5
  • Empirical Formula: C22H28FNa2O8P
  • Molecular Weight: 516.4
  • MDL number: MFCD00200361
  • EINECS: 205-797-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-13 18:13:23
Betamethasone 21-phosphate disodium Structural

What is Betamethasone 21-phosphate disodium?

Chemical properties

White or almost white powder, very hygroscopic.

The Uses of Betamethasone 21-phosphate disodium

Betamethasone 21-Phosphate Disodium Salt (Dexamethasone Sodium Phosphate EP Impurity B) is a Betamethasone derivative. It is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.

The Uses of Betamethasone 21-phosphate disodium

Nasal, Ophthalmic, Oral, Parenteral

What are the applications of Application

Betamethasone 21-phosphate sodium salt is an anti-inflammatory agent

Definition

ChEBI: An organic sodium salt that is the disodium salt of betamethasone phosphate.

brand name

Celestone (Schering).

Biochem/physiol Actions

Betamethasone is used to treat neonatal respiratory distress syndrome, and psoriasis.

Safety Profile

Moderately toxic by ingestion andother routes. An experimental teratogen. Otherexperimental reproductive effects. When heated todecomposition it emits toxic fumes of F??, POx and Na2O.

Properties of Betamethasone 21-phosphate disodium

Melting point: 206-211°C
alpha  +98.0~+104.0°(D/20℃)(c=1,H2O) (calculated on the dehydrous basis)
storage temp.  room temp
solubility  Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
form  neat
form  Solid
color  White to Off-White
PH 7.5~9.0(5g/l, 25℃)
Merck  14,1180
Stability: Hygroscopic
EPA Substance Registry System .beta.-Methasone disodium phosphate (151-73-5)

Safety information for Betamethasone 21-phosphate disodium

Signal word Danger
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H302:Acute toxicity,oral
H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for Betamethasone 21-phosphate disodium

InChIKey PLCQGRYPOISRTQ-LWCNAHDDSA-L
SMILES [C@@]12([H])C[C@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H].[Na+].[Na+] |&1:0,3,5,15,18,20,22,32,r|

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