Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listbeta-Cyclodextrin hydrate

beta-Cyclodextrin hydrate

Synonym(s):β-Schardinger dextrin;beta-Cyclodextrin hydrate;Cycloheptaamylose;Schardinger β-Dextrin hydrate

  • CAS NO.:68168-23-0
  • Empirical Formula: C42H70O35
  • Molecular Weight: 1134.98
  • MDL number: MFCD00150811
  • EINECS: 231-493-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-12 18:14:22
beta-Cyclodextrin hydrate Structural

What is beta-Cyclodextrin hydrate?

Description

β-Cyclodextrin (β-CD) is a cyclic oligosaccharide that contains seven D-(+)-glucopyranose units and has been used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.

Chemical properties

white crystalline powder

The Uses of beta-Cyclodextrin hydrate

beta-Cyclodextrin hydrate forms clathrates. Produces a water-soluble complex with dansyl chloride for the fluorescent labeling of proteins. It is used in pharmaceutical research, as pharmaceutical intermediates and also as chemical reagents.

General Description

β-cyclodextrin (β-CD), a well-known macrocyclic oligosaccharide member of the CD family, is composed of seven D-glucose units connected via α(1→4) glycosidic bonds. Its ability to form several inclusion complexes with organic as well as inorganic compounds makes it a potential candidate in solid and solution state determinations.

Purification Methods

Recrystallise β-cyclodextrin from water and dry it for 12hours in a vacuum at 110o, or 24hours in a vacuum at 70o. The purity is assessed by TLC on cellulose containing a fluorescent indicator. [Taguchi, J Am Chem Soc 108 2705 1986, Tabushi et al. J Am Chem Soc 108 4514 1986, Orstam & Ross J Phys Chem 91 2739 1987.] [Beilstein 19 IV 6287, 19/12 V 801.]

Properties of beta-Cyclodextrin hydrate

Melting point: >260 °C (dec.)(lit.)
alpha  161 º (c=1, H2O 25 ºC)
storage temp.  Refrigerator
solubility  Water (Slightly)
form  Crystalline Powder
color  White
optical activity [α]20/D +142°, c = 1 in H2O (Dry basis)
Water Solubility  18.5 g/L (25 ºC)
Merck  14,2718
BRN  5915513

Safety information for beta-Cyclodextrin hydrate

Computed Descriptors for beta-Cyclodextrin hydrate

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.