Benserazide hydrochloride
Synonym(s):DL -Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
- CAS NO.:14919-77-8
- Empirical Formula: C10H16ClN3O5
- Molecular Weight: 293.7
- MDL number: MFCD00078571
- EINECS: 238-991-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:46
What is Benserazide hydrochloride?
Description
Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It is also unable to cross the blood-brain barrier. As a result, benserazide blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. Benserazide is often combined with L-DOPA in patients with Parkinson’s disease.
The Uses of Benserazide hydrochloride
Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a peripheral decarboxylase inhibitor. It is used as an inhibitor for aromatic L-aminoacid decarboxylase. Further, it serves as an inhibitor of tyrosine hydroxylase (TH) and Tryptophan hydroxylase (TPH) inhibitor.
What are the applications of Application
Benserazide?HCl (Ro 4-4602) is an aromatic L-aminoacid decarboxylase inhibitor
Properties of Benserazide hydrochloride
Melting point: | 146°C |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL |
form | solid |
color | White to Off-White |
Water Solubility | Soluble in water, dimethyl sulfoxide and methanol. Insoluble in ethanol and acetone. |
Sensitive | Light Sensitive |
Safety information for Benserazide hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Benserazide hydrochloride
InChIKey | ULFCBIUXQQYDEI-UHFFFAOYSA-N |
Abamectin manufacturer
Lifecare Laboratories Pvt. Ltd
Biophore India Pharmaceuticals Pvt Ltd
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