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14919-77-8

14919-77-8 structural image
Product Name: Benserazide hydrochloride
Formula: C10H16ClN3O5
Synonyms: DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
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CHEMICAL AND PHYSICAL PROPERTIES

Solubility 35.4 [ug/mL] (The mean of the results at pH 7.4)

SAFETY INFORMATION

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight 293.70 g/mol
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 5
Exact Mass 293.0778483 g/mol
Monoisotopic Mass 293.0778483 g/mol
Topological Polar Surface Area 148 Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 278
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Benserazide hydrochloride is a hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions when given alone. It has a role as an antiparkinson drug, an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor and a dopaminergic agent. It contains a benserazide(1+).

RELATED SUPPLIERS

Lifecare Laboratories Pvt. Ltd

1Y
product:14919-77-8 / 14046-64-1 Benserazide hydrochloride 98%

Biophore India Pharmaceuticals Pvt Ltd

1Y
product:14919-77-8 / 14046-64-1 98%
All suppliers(2)