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HomeProduct name listBenmoxine

Benmoxine

Benmoxine Structural

What is Benmoxine?

Originator

Neuralex,Millot

Definition

ChEBI: Benmoxin is a member of benzoic acids.

Manufacturing Process

A mixture of 29.6 parts of acetylhydrazine, 48 parts of acetophenone and 140 parts of ethanol is heated under reflux for 18 hours and is then cooled to 20-25°C and filtered. The solid residue, M.P. 135-136°C, is washed with diethyl ether and dried at 40°C. 28.5 parts of this dried product in 180 parts of methanol is shaken in an atmosphere of hydrogen under a pressure of 100 atmospheres and at a temperature of 25°C in the presence of 3 parts of a 5% palladium on carbon catalyst until the theoretical amount of hydrogen is absorbed. The mixture is filtered and the filtrate is evaporated. The residue is fractionally distilled under reduced pressure and there is thus obtained 1-(α- methylbenzyl)-2-acetylhydrazine, B.P. 182-186°C/15 mm, M.P. 72-74°C.

Therapeutic Function

Antidepressant

Properties of Benmoxine

Melting point: 93-94°
Boiling point: 383.02°C (rough estimate)
Density  1.0611 (rough estimate)
refractive index  1.6390 (estimate)
pka 12.29±0.23(Predicted)

Safety information for Benmoxine

Computed Descriptors for Benmoxine

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