BAY 299

CAS NO.：2080306-23-4
Empirical Formula: C25H23N3O4
Molecular Weight: 429.47
MDL number: MFCD30480933
Update Date: 2024-10-30 21:47:27

What is BAY 299?

Description

BAY-299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 (IC₅₀ = 6 nM), also known as BRPF2, and the second bromodomain of transcription initiation factor TFIID subunits 1 (TAF1; IC₅₀ = 13 nM). BAY-299 is >30-fold selective over BRPF1, BRPF3, BRD9, and ATAD2 and is >300-fold selective over BRD4. See the Structural Genomics Consortium (SGC) website for more information.

The Uses of BAY 299

BAY 299, is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1, also known as BRPF2, and a strong inhibitor of TAF1/TAF1L BD2. These proteins play important roles in transcription regulation.

storage

Store at -20°C

Properties of BAY 299

Boiling point:	688.7±55.0 °C(Predicted)
Density	1.377±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:30.0(Max Conc. mg/mL);69.85(Max Conc. mM) DMF:30.0(Max Conc. mg/mL);69.85(Max Conc. mM)
form	A crystalline solid
pka	14.98±0.10(Predicted)
color	Light yellow to yellow