Azido-PEG8-NHS ester
- CAS NO.:1204834-00-3
- Empirical Formula: C23H40N4O12
- Molecular Weight: 564.5833
- MDL number: MFCD13184949
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:11
What is Azido-PEG8-NHS ester?
Description
Azido-PEG8-NHS ester is a popular click chemistry reagent with an azide and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
The Uses of Azido-PEG8-NHS ester
Azido-PEG8-NHS ester series of products contain an azide function on one end of a single molecular weight dPEG? spacer and a reactive group on the other end of the spacer. The dPEG? spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target.
Properties of Azido-PEG8-NHS ester
storage temp. | -20°C |
solubility | Soluble in DMSO, DCM, DMF |
form | solid or viscous liquid |
color | Colorless to light yellow |
Safety information for Azido-PEG8-NHS ester
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Azido-PEG8-NHS ester
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