AYANIN

CAS NO.：572-32-7
Empirical Formula: C18H16O7
Molecular Weight: 344.32
MDL number: MFCD03844820
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

What is AYANIN?

The Uses of AYANIN

Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase inhibitor.

Definition

ChEBI: 3',5-dihydroxy-3,4',7-trimethoxyflavone is a trimethoxyflavone that is quercetin in which the hydroxy groups at positions 3, 4' and 7 have been replaced by methoxy groups. It has a role as a plant metabolite. It is a dihydroxyflavone and a trimethoxyflavone. It is functionally related to a quercetin. It is a conjugate acid of a 3',5-dihydroxy-3,4',7-trimethoxyflavone(1-).

Biological Activity

Ayanin is a biologically active flavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase (phosphodiesterase1-4) inhibitor, which can be used in the study of respiratory diseases, such as allergic asthma.

in vitro

Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC ₅₀ value of 2.2 μM.

Properties of AYANIN

Melting point:	173℃
Boiling point:	600.8±55.0 °C(Predicted)
Density	1.45±0.1 g/cm3(Predicted)
storage temp.	4°C, protect from light
form	Solid
pka	6.15±0.40(Predicted)
color	White to yellow